Introduction Knee osteoarthritis is one of the most common joint disorders worldwide and a leading cause of pain and disability among adults. This condition occurs when the protective cartilage that cushions the ends of the bones within the knee joint gradually wears away over time. As the cartilage deteriorates, the bones begin to rub against each other, causing pain, stiffness, swelling, and reduced mobility. Millions of people suffer from knee osteoarthritis, and its prevalence continues to rise due to aging populations, increasing obesity rates, and sedentary lifestyles. Although osteoarthritis is commonly associated with older adults, younger individuals may also develop the condition as a result of injuries, genetic factors, or excessive stress on the joint. This comprehensive guide explores everything you need to know about knee osteoarthritis, including its causes, symptoms, diagnosis, treatment options, prevention strategies, and the latest medical advancements. What is ...
Cancer Undefeated Abstract BACKGROUND Despite decades of basic and clinical research and trials of promising new therapies, cancer remains a major cause of morbidity and mortality. We assessed overall progress against cancer in the United States from 1970 through 1994 by analyzing changes in age-adjusted mortality rates. METHODS We obtained from the National Center for Health Statistics data on all deaths from cancer and from cancer at specific sites, as well as on deaths due to cancer according to age, race, and sex, for the years 1970 through 1994. We computed age-specific mortality rates and adjusted them to the age distribution of the U.S. population in 1990. RESULTS Age-adjusted mortality due to cancer in 1994 (200.9 per 100,000 population) was 6.0 percent higher than the rate in 1970 (189.6 per 100,000). After decades of steady increases, the age-adjusted mortality due to all malignant neoplasms plateaued, then decreased by 1.0 percent from 1991 to 1994. The decline in mort...